Chemerin as a cardiovascular biological marker: Present and future

Cardiovascular diseases are the leading cause of invalidity and mortality in majority developed countries recognized by international community as a pandemic problem. An important task modern cardiology is search study new biological markers.
 This literature review aimed to consider chemerin diagnostic prognostic marker for cardiovascular pathologies. Thus far, studies on indicate possibility its use pathology. Evidence points role development progression diseases. As an adipokine, modulates glucose, lipid levels, thereby influencing deposition endothelium atherosclerosis. chemoattractant, it facilitates mobilization interaction macrophages with dendritic cells natural killer vascular system induces endothelial angiogenesis. The established inflammation, angiogenesis, blood pressure modulation opens serious prospects therapeutics targeting this biomarker treatment Several candidates CMRK1 signaling pathway have shown promising potential reducing dysfunction vitro vivo studies. Further analyzing efficacy safety chemerin-targeting drugs needed assess their potential.